The top trend last week was that Andrew Luck and the Colts were likely to bounce back from their Week 1 loss. How'd that turn out? Just a 12-point win as 6-point underdogs!
This week's slate features a 16.5-point favorite, and the trends actually suggest that laying the points is the smart play.
Here are the rest of the trends that should help you in betting the NFL this weekend.
All lines are courtesy of Westgate Las Vegas SuperBook.
Favorites are 11-2 against the spread in the past 13 games with a spread of at least 14 points.
The Vikings are 25-9-1 ATS in their 35 home games under head coach Mike Zimmer.
Jimmy Garoppolo is 4-1 ATS with four outright wins in five career starts as an underdog.
The Chiefs have lost outright in six of their past nine games as a favorite.
Carson Wentz is 11-3 ATS and 12-2 straight up in 14 career home starts.
The Colts are 2-7-1 ATS in their past 10 games following a straight-up win.
The Panthers are 5-1 ATS and 6-0 SU in their past six home games.
The Bengals have covered in four straight games dating back to last season. Cincinnati hasn't covered in five straight since 2011.
The Jaguars are 6-1 ATS in their past seven home games against the Titans.
The underdog is 7-2 ATS with five outright wins in the past nine meetings between these division rivals.
The under is 8-1 in the Falcons' past nine games.
The Broncos are 1-9 ATS in their past 10 road games.
The under is 8-1 in the Giants' past nine games.
The under is 9-2 in the Texans' past 11 games.
The under is 9-0 in the Raiders' past nine games.
The Raiders are 2-5-1 ATS with no outright wins in their past eight games as an underdog.
The over is 24-7 in the Packers' past 31 games, including 14-2 on the road during this span.
The Redskins have won outright in seven of their past 11 games as a home underdog.
Philip Rivers is 11-3 ATS with five outright wins in his career when listed as an underdog of at least 7 points.
The Chargers are 15-6-2 ATS in their past 23 road games.
This will mark the second time the Bears are favored in their past 35 road games. The other game was in Week 10 of the 2016 season, when Chicago lost 36-10 as 2.5-point favorites at Tampa Bay.
The under is 16-5 in the Cardinals' past 21 home games.
Dak Prescott is 8-2-1 ATS and 9-2 SU in 11 career starts against teams with a losing record.
The under is 10-1 in the Cowboys' past 11 games.
Tom Brady is 38-15 ATS in his career in games after a loss.
The over is 8-2 in the Lions' past 10 home games.