Valencia's Carlos Soler had a hand in all three goals as they beat Young Boys 3-1 in the Champions League on Wednesday.
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Guillaume Hoarau equalised for Young Boys to give the Swiss champions their first ever point in competition history.
Paulo Dybala flourished in the absence of suspended Cristiano Ronaldo on Tuesday, scoring a hat-trick to give the Serie A champions a 3-0 win.
Cristiano Ronaldo was red carded 29 minutes into his Champions League debut for Juventus against Valencia after clashing with Jeison Murillo.
With two goals and an assist, Paul Pogba led by example as Jose Mourinho's men eased past Young Boys. New signing Diogo Dalot enjoyed a fine debut.
Paul Pogba scored twice as Manchester United spoiled Young Boys' first appearance in the group stage of the Champions League with a 3-0 victory.
Young Boys have been the eternal losers of Swiss football over the last three decades. Now they have a league title and a spot in the UCL groups.
Juventus will face Man United in the Champions League group stage this season, giving Cristiano Ronaldo a chance to play against his former team.
Ajax qualified for the Champions League group stage on Tuesday for the first time in four years. AEK Athens and Young Boys also booked their spots.
Eintracht Frankfurt have announced Adi Hutter will replace Niko Kovac as head coach at the end of the season.
Liverpool earned a first-leg away win at Hoffenheim while CSKA needed a fortunate own goal to edge Young Boys.
Borussia Monchengladbach have signed midfielder Denis Zakaria from Young Boys in a deal reportedly worth about €10 million.
Orlando City completed the signing of right-back Scott Sutter from Swiss club Young Boys on Friday.
Young Boys striker Guillaume Hoarau says he rejected a January switch to Lyon because playing in Switzerland means he can also focus on his music.
Manchester United's troubles away from home in Europe continued in a 2-1 defeat at Fenerbahce in the Europa League as Paul Pogba limped off injured.
Manchester United laboured to a 1-0 Europa League victory over Zorya Luhansk at Old Trafford as Zlatan Ibrahimovic headed home in the second half.
Manchester City secured their place in the Champions League group stage with a 1-0 win over Steaua Bucharest, while Rostov eliminated Ajax.
Newcastle defender Kevin Mbabu is to return to his native Switzerland to spend the season on loan at Young Boys.
The Foals will play the first leg away at the Stade de Suisse on Aug. 16-17. The second leg will take place at the Borussia Park on Aug. 23-24.
Shakhtar Donetsk, Olympiakos and Fenerbahce all crashed out of the UEFA Champions League in the third qualifying round on Wednesday.
Shakhtar Donetsk began their Champions League campaign with a 2-0 win over Young Boys in the third qualifying round on Tuesday.
The draw for the third qualifying round of the Champions League and some of the bigger clubs join the competition.
Manchester United could face a tricky Champions League playoff against the likes of CSKA Moscow, Lazio, Monaco or Sporting Lisbon in August.