The Atlas Lions are on the brink of the 2019 Africa Cup of Nations after securing a 2-0 victory on Friday.
The Pharaohs defeated the Carthage Eagles 3-2 in a North African derby on Friday, with Mohamed Salah netting a late winner.
While a defeat to Nigeria wouldn't be a disaster for South Africa, the AFCON qualifier has the feel of a pivotal moment for the country's football.
Zimbabwe are on the brink of reaching the 2019 Africa Cup of Nations, but can they sustain this success?
Despite his fine form, Henry Onyekuru is unlikely to start for Nigeria in this weekend's Africa Cup of Nations qualifier against South Africa.
For the first time since September 2015, Nigeria approach a match without any of their three first-choice midfielders in a matchday squad.
Zimbabwe face a stern test when they travel away to Liberia in Sunday's Africa Cup of Nations qualifier.
Tickets are not selling well for Bafana Bafana's crucial AFCON qualifier against Nigeria at FNB Stadium on Saturday, a big red flag for SAFA.
The Chelsea forward's retirement came as something of a shock, but Gernot Rohr's has made the most of a tricky situation.
Which are the key areas that could decide the Super Eagles' showdown with Bafana Bafana at the FNB Stadium?
Talent Chawapiwa believes Zimbabwe's formidable fire power can 'punish' Liberia in Sunday's Africa Cup of Nations qualifier.
Despite the high-profile call-ups to the Ghana fold, it's Thomas Partey who remains the Black Stars' best hope.
Tinotenda Kadewere's return to full fitness after four months out with a knee complaint should prove a great lift for Zimbabwe.
It is a sign of South Africa's injury crisis and rapid evolution that just nine of their 23-man squad have ever faced Nigeria before.
Montpellier defender Ambroise Oyongo has been ruled out of the Cameroon squad to face Morocco in Friday's Africa Cup of Nations qualifier.
Nigeria may be in pole position in Group E, but they're up against it in Johannesburg if they're to avoid a repeat of recent unhappy memories.
The Black Stars have revealed that the Internazionale midfielder will not be involved in the Africa Cup of Nations qualifier against Ethiopia.
KweséESPN breaks down Nigeria's available options in goal and at centre-forward ahead of the all-important qualifying clash against South Africa.
Odion Ighalo tells KweséESPN he is "devastated and sad" after suffering an injury that has effectively ended his season.
Kwesi Appiah's latest Ghana squad has highlighted the severity of one of the Black Stars' longest standing problems.
Galatasary forward Henry Onyekuru has been called up from the standby list to replace Odion Ighalo ahead of Nigeria's AFCON qualifier vs Bafana.
The Ayew brothers are set to end their year-long absence from the Black Stars squad after being called up for the Ethiopia clash.
Hearts midfielder Arnaud Djoum has been named in Cameroon's squad for their Africa Cup of Nations qualifier against Morocco on November 16.
Thulani Serero's return to Bafana Bafana for the AFCON qualifier vs. Nigeria came as a welcome surprise, and one that finally sees sanity prevail.
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