Ernesto Valverde picked a team of youngsters and squad players against Cultural Leonesa. Some responded to the call, others did not.
Holders Barcelona scraped a 1-0 win at third-tier Cultural Leonesa thanks to Clement Lenglet's late header in their Copa del Rey first-leg match.
Alvaro Odriozola's composed performance in Real Madrid's Copa del Rey win over Melilla suggested the potential for a larger role under Santi Solari.
Solari said the decisive win in his first game in temporary charge was "the fruit" of his players' positivity and commitment.
Santiago Solari got off to the perfect start as Real Madrid's interim coach when his side thrashed Melilla 4-0 in the Copa del Rey on Wednesday.
Gelson Martins netted his first goal for Atletico Madrid to help Diego Simeone's side scrape a 1-0 win at fourth-tier Sant Andreu on Tuesday.
Ernesto Valverde will hand opportunities to Barcelona's fringe players and youngsters when they travel to Cultural Leonesa in the Copa del Rey.
Real Madrid will travel to Spain's African enclave of Melilla to open the Copa del Rey, the first to include the top two tiers of Spanish clubs.
Curtain raiser has been a two-legged contest in the past but a tight schedule has led to a change this time around.
Barcelona celebrated their La Liga and Copa del Rey titles on Monday with a parade through the city's streets.
Real Madrid's Sergio Ramos says that his team lifting the Champions League would be worth "maybe a little more" than Barcelona's domestic double.
Sevilla midfielder Steven N'Zonzi has apologised for partying in Madrid hours after his side's 5-0 loss to Barcelona in the Copa del Rey final.
Barcelona captain Andres Iniesta says he will announce his future plans in the coming week after receiving a offer to play in China.
Barcelona captain Andres Iniesta scored a goal and rated 9/10 in the Copa del Rey final vs. Sevilla, in what was likely his last final with Barca.
Barcelona coach Ernesto Valverde said he'd have "given his arm" for the touch of Andres Iniesta after a Copa del Rey finals win against Sevilla.
Luis Suarez said Barcelona's Copa del Rey triumph sets the team up for a Copa and Liga double they would have accepted at the start of the season.
Barcelona picked a poor Sevilla apart in the Copa del Rey final, as Andres Iniesta turned back the clock to treat the fans to one final masterpiece.
Barcelona made short work of Sevilla in the Copa del Rey final, with Luis Suarez scoring twice as the La Liga leaders earned a record-tying 5-0 win.