1 p.m. ET | FOX
Matchup rating: 42.7 | Spread: CLE -2.5 (51)
What to watch for: How will the Browns' offense respond minus star receiver Odell Beckham Jr., who is out for the season with a knee injury? Beckham leads the team in targets. Quarterback Baker Mayfield will have to find a connection elsewhere, as he now has 10 straight games with a TD pass, the second-longest streak of his career (17 games from 2018 to '19). -- Jake Trotter
Bold prediction: The Raiders, bolstered by the return of right tackle Trent Brown, will shut out the league's leading sack master in Browns defensive end Myles Garrett, who already has nine sacks and has had a sack in six straight games. -- Paul Gutierrez
Stat to know: Cleveland running back Kareem Hunt has seven scrimmage touchdowns this season. The Browns are 5-0 when Hunt scores but 0-2 in games in which he fails to find the end zone.
What to know for fantasy: Mayfield averaged 1.07 fantasy points per pass attempt in the big win over the Bengals, more than 2.5 times his season rate prior to the game. See Week 8 rankings.
Betting nugget: All six Raiders games this season have gone over the total. The longest over streak from the start of a season was the 2002 Saints, who started the season with nine consecutive overs. Read more.
Gutierrez's pick: Raiders 28, Browns 27
Trotter's pick: Browns 27, Raiders 26
FPI prediction: CLE, 55.2% (by an average of 1.8 points)
Matchup must-reads: Revisiting Raiders-Browns and 'Red Right 88': 'That was a hell of a play in our history' ... Browns not better without OBJ, but Mayfield might be ... Despite blowout loss, Raiders find silver (and black) linings in strange week ... Big Ben and the Heismans -- Sizing up AFC North's QBs