1 p.m. ET | FOX
Matchup rating: 33.5 | Spread: DET -3 (44)
What to watch for: Bears starter Mitchell Trubisky has shredded the Lions' defense over the past two seasons, throwing nine touchdowns and one interception. Detroit has the same head coach (Matt Patricia) but a new defensive coordinator (Cory Undlin). Whether or not Trubisky continues to complete passes at a 74.7% clip against Detroit will be the difference. -- Michael Rothstein
Bold prediction: Chicago's offense scores a touchdown on its opening drive. Crazy, right? The Bears' offense struggled horribly in the first quarter last year. In Chicago's first eight games of 2019, the Bears scored one touchdown and punted an NFL-worst seven times on opening drives, and they ended the year with 37 first-quarter points. Will the Bears' offense rise from the ashes with Trubisky back at quarterback? Well, probably not. But he is usually pretty good versus the Lions. -- Jeff Dickerson
Stat to know: The 2019 Bears' offense ranked No. 31 in yards per play (4.7), No. 29 in points per game (17.5) and No. 27 in offensive efficiency (35.4). In all, it had nine games with fewer than 20 points last season, tied for fourth-most in the NFL. Part of the reason was Trubisky's drop in Total QBR from 2018, a plummet that ranked second-worst behind only his new backup, Nick Foles (minimum 100 pass attempts).
What to know for fantasy: Chicago wide receiver Allen Robinson II scored 104.9 fantasy points in divisional games last season, ranking him fourth at the position (behind only Michael Thomas, Chris Godwin and Robert Woods). See Week 1 rankings.
Betting nugget: Detroit has nine straight seasons of hitting the over in its season opener, the longest active streak in the league. And the Bears were 1-7 ATS on the road last season and failed to cover in 10 of last 12 games overall. Read more.
Dickerson's pick: Bears 17, Lions 16
Rothstein's pick: Lions 23, Bears 17
FPI prediction: CHI, 55.1% (by an average of 1.9 points)
Matchup must-reads: Bears running game has question marks ... What does signing Peterson mean for the Lions? ... Mack determined to improve on substandard 2019 ... Stafford's 'photographic' memory helps him master Lions' offense