The Gamecocks announced the schedule addition Friday.
South Carolina was scheduled to face Marshall on Sept. 15 but called the game off midweek as the Category 4 storm approached the North and South Carolina coast. The storm has been blamed for the deaths of at least 49 people across several states.
Akron was available because its Sept. 1 contest at Nebraska was canceled due to lightning. The game will kick off at noon ET at Williams-Brice Stadium.