Egypt and Senegal qualified for the African Nations Cup thanks to wins against Tanzania and Burundi.
First-half goals from Premier League duo Sadio Mane and Mame Biram Diouf sealed a 2-0 win for Senegal at Burundi and ensured they will win Group K, having won five games from five, scoring 11 times and conceding just twice.
The other game in that group saw Namibia run out 1-0 winners against Niger with Peter Shalulile's 15th-minute goal settling the game.
Meanwhile, a Mohamed Salah brace resolved Egypt's game in Tanzania and left them eight points clear of Nigeria in three-man Group G with one game to play.
Cape Verde's 2-1 win against Sao Tome and Principe was in vain as Morocco have already qualified from Group F, but they are in a good position to take one of the two places reserved for the best runners-up.
In Group H, Rwanda's 3-2 reverse against Mozambique means they cannot reach leaders Ghana, who play Mauritius on Sunday. But should Avram Grant's Black Stars slip up they can still be overtaken by their opponents.
Mali, who won 3-0 at South Sudan, could qualify for the tournament on Sunday if Benin fail to beat Equatorial Guinea.
Uganda moved into pole position in Group D courtesy of a 2-0 win at Botswana but they can be pegged back by Burkina Faso, who face bottom side Comoros on Sunday.
Should Congo lose to Kenya on Sunday, Guinea Bissau will qualify from Group E after beating Zambia 3-2.
Sierra Leone beat Sudan 1-0 which leaves them a point behind Ivory Coast in Group I, with the two nations meeting in the final round of games in September.
South Africa beat Gambia 4-0 in Group M, which leaves the Bafana Bafana with slim hopes of taking one of the best runners-up places in a group already won by Cameroon.