Gerard Deulofeu scored on a sharp free kick but Everton lost to Dynamo Dresden in their first game of the Dresden Cup on Friday night.
Erich Berko scored from close range for the German second-division team before Deulofeu equalised with a free kick that grazed the underside of the bar.
Everton seemed to be in control in the second half but against the run of play Pascal Testroet stunned the Toffees with a 25-yard shot that went in off the post.
John Stones played 70 minutes despite transfer speculation linking him to a move to Manchester City.
In the earlier game at the Dresden Cup, Nahuel scored the only goal in the 67th minute as Real Betis earned a 1-0 win against Werder Bremen. Everton will face Real Betis on Saturday, while Bremen go up against the hosts.
Bournemouth, the only other Premier League side in action on Friday, were held to a 1-1 draw at Reading.
Lewis Cook opened the scoring for the Cherries before the break before John Swift equalised five minutes into the second half.
In addition to Bremen's loss, it was a rough day across the board for Bundesliga sides, with all four teams in action suffering defeats.
Huddersfield Town surprised Ingolstadt 1-0, Kasey Palmer scoring the only goal four minutes from time after U.S. international Alfredo Morales was sent off.
Augsburg also lost, stumbling to a 2-1 defeat to Nurnberg. Paul Verhaegh's converted a penalty on the hour mark for Augsburg, but the hosts erased the lead three minute later through Edgar Salli before Guido Burgstaller scored the winner from the spot.
Hamburg completed the misery with a 1-0 loss at Bochum after they could not match Peniel Mlapa's third-minute goal.
Fiorentina fell to Serie B side Cesena 2-0 after conceding goals to Antonio Ragusa and Milan Djuric.
Udinese defeated Turkey's Akhisar Belediyespor 2-1 with goals from Duvan Zapata and Gabriele Angella.
Massimo Maccarone scored four times as Empoli rolled to 12-0 win over amateurs Montelupo.
Aston Villa loanee Carles Gil scored twice to give Deportivo La Coruna a 2-0 win over Racing de Ferrol.
Srdjan Babic and Juanmi scored either side of half-time to give Real Sociedad a 2-0 win at NEC Nijmegen.
Las Palmas cruised to a 4-1 win at third-tier La Hoya Lorca thanks to goals from Angel Montoro, Marko Livaja, Alfredo Ortuno and Momo.
Toulouse came out on top 2-1 over Nice in a friendly between two Ligue 1 teams.
With all the goals coming in a nine-minute span, Nice's Alexy Bosetti cancelled out Oscar Trejo's opener before Martin Braithwaite found the winner.
Bastia fell to a 4-1 defeat against Eintracht Braunschweig, who got a pair of goals from Dominik Kumbela either side of Yannick Cahuzac's red card.
Metz managed a 1-1 draw with Kaiserslautern, as Guido Milan opened the scoring for the newly promoted Ligue 1 side before Osayamen Osawe's equaliser.