The Indians announced Wednesday that an MRI confirmed that Carrasco is "dealing with mild right elbow inflammation."
Carrasco had an anti-flammatory injection and will not throw for a few days.
The 32-year-old Carrasco missed three months last season battling chronic myeloid leukemia. He appeared in 23 games and went 6-7 with a 5.29 ERA.
He came to camp looking to regain the form that saw him win a league-leading 18 games in 2017 and 17 the next season.