Irving has been dealing with a right shoulder impingement and had been questionable to play in Thursday's contest against the Denver Nuggets. He received treatment and posted 17 points, nine assists and six rebounds in 35 minutes during the 101-93 Nets loss.
This will be Irving's first missed game since joining the Nets in the offseason. Brooklyn finishes a five-game road trip -- on which it is 1-3 so far -- against Chicago and next plays Monday against the Indiana Pacers.
Irving leads the Nets in scoring (28.5 PPG), assists (7.2) and minutes (33.8).