Morse will miss Wednesday's practice.
Morse's concussion was diagnosed Tuesday but occurred during Saturday's practice -- the Bills' first in full pads. Although it occurred Saturday, Morse's symptoms were not immediately discernible.
"Anytime a player is injured, I am concerned because: A) it's their health and B) it's the health of our overall football team," McDermott said. "You've heard me say how important availability is, so we've got to make sure that we get these guys back, and just overall the number of guys we've got out right now is concerning. We can only control what we can control, so that's what we focus on and it does give other guys the opportunity to step up and show us what they've got."
Morse, 27, took a rest day Sunday before the team's off day Monday. He worked to the side during Tuesday's practice, when it was ultimately decided he be placed in concussion protocol.
The Bills made Morse the league's highest-paid center this offseason with a four-year, $44.5 million contract. Formerly of the Chiefs, Morse has had three documented concussions during his four-year career. He missed five games because of them last season.
There's no immediate timeline for Morse's return; he will be evaluated day-by-day.