France's Wesley Fofana and Bernard Le Roux have been ruled out of the upcoming November internationals with injuries.
Centre Fofana has failed to recover from a thigh problem sustained in September, while forward Le Roux picked up a facial injury in Racing 92's victory over Ulster in the European Champions Cup Saturday.
Toulouse wing Johan Huget and Lyon second row Felix Lambey have been called up as replacements.
The experienced Huget has earned 51 France caps, scoring seven international tries in the process, while Lambey is in line for just his second cap after making his debut against New Zealand in June.
France face South Africa on Nov. 10 in Paris, then move on to Lille to play Argentina a week later and conclude back in Paris against Fiji on Nov. 24.