England have included eight uncapped players in their starting lineup to play the United States at Twickenham on Sunday, with Harlequins Marcus Smith named at fly-half.
Coach Eddie Jones has put together a team for the future with several players away with the British & Irish Lions or being rested for the summer.
Smith will make his England debut on Sunday, fresh from steering Harlequins to the Premiership title.
Scrumhalf Harry Randall also makes his debut as does blindside flanker Lewis Ludlow, who will captain the team. Prop Ellis Genge will be vice-captain, while centre Henry Slade, with 38 caps, is the most experienced player in the side.
A further four uncapped players are among the replacements, including Ben Curry, brother of Tom, who is in South Africa with the Lions.
"Over the past three weeks our biggest message to the players is what an opportunity this is to show what they can do and make their mark with England," Jones said in a statement.
"They've applied themselves as a group and worked very hard individually during this camp to reach their personal bests. Now it's all about coming together as a team, gelling and putting in a good performance at the weekend."
After Sunday's game England play Canada the following Saturday. Both games had originally been scheduled as away games but were switched to Twickenham due to COVID-19 travel restrictions.
England team for United States:
Freddie Steward, Joe Cokanasiga, Henry Slade, Ollie Lawrence, Max Malins, Marcus Smith, Harry Randall, Ellis Genge, Curtis Langdon, Joe Heyes, Josh McNally, Charlie Ewels, Lewis Ludlow (captain), Sam Underhill, Callum Chick.
Jamie Blamire, Beno Obano, Trevor Davison, Ted Hill, Ben Curry, Lewis Ludlam, Dan Robson, Jacob Umaga.