Anthony Tuitavake was sent off as Racing 92 lost 23-19 at Agen in the Top 14.
La Rochelle climb into Clermont's buffer in the Top 14 standings as Zack Holmes kicks 20 points in 25-19 win over Toulouse.
A Ben Botica penalty three minutes into stoppage time saw Montpellier record a 12-11 victory over La Rochelle.
Edinburgh edged past Harlequins 36-35 in thrilling encounter in the European Challenge Cup.
- BRIV12thTries Scored 1st Lyon : 45 Tries ScoredLYON1st2645
- BRIV9thPoints Difference 1st Lyon : 182 Points DifferenceLYON1st-58182